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Sight is invaluable. Our aim is to improve quality of life through renewal and restorative practices by assisting scientists and researchers in their quest for the game changer in eye health


Ophthalmic Trials Australia was grown from more than 20 years in optometry and specialist fields within Mark Hinds optometry and collaboration with ophthalmology our portfolio brings a wealth of knowledge and experience. The ever-growing database of over 13 000 patients over many years of professional networking sees patients referred from a broad range of age, ethnic, genetic and lifestyle backgrounds. Our collaboration with both private and public ophthalmology facilitates the opportunity to delve into their extensive resources and patient base. Our drive to conduct trials for targeted research to save sight and bring a change to quality of life for many is our passion and focus.

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Our clinical trial program facilitates the new and leading treatments for patients with and without eye conditions improve clinical outcomes and patient quality of life.
Evidenced based medicine requires diligent assessment of findings through Clinical Trials. Ophthalmic Trials Australia’s research is intent on improving the current suite of ophthalmic resources clinical practice has at is fingertips in the effort to restoring or at least, maintaining visual function. By taking time out of daily practice Mark Hinds’ team has developed Ophthalmic Trials Australia to allow medical providers to offer further clinical recommendations due to increased necessary publications and the end user new medications and innovations in clinical practice.

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Meet one of our lead investigators.

Mark Hinds – BIO 2021
BScApp(Optom) (Queensland University of Technology)
GradCertOcTher (Queensland University of Technology)
BScApp(HMS) (University of Queensland)
P/G BscHons – Exercise Physiology (University of Queensland)
FBCLA (Manchester)

CASA Credentialled Optometrist

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According to the National Health and Medical Research Council (Department of Industry, Innovation and Science) as published by the Australian Government this is what a clinical trial is:
Clinical trials are research investigations in which people volunteer to test new treatments, interventions or tests as a means to prevent, detect, treat or manage various diseases or medical conditions. Some investigations look at how people respond to a new intervention and what side effects might occur. This helps to determine if a new intervention works, if it is safe, and if it is better than the interventions that are already available.

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Most (but not all) of the clinical trials through Ophthalmic Trials Australia are Phase 1 clinical trials where after ethics approvals we conduct a series of tests on a smaller group (20-80) of participants. As a rule, most pharmacological and biomedical interventions for clinical trials follow from Phase 1 to Phase 4 as per:

Phase I Clinical Trial

Phase I clinical trials are done to test a new biomedical intervention for the first time in a small group of people (e.g. 20-80) to evaluate safety (e.g. to determine a safe dosage range and identify side effects).

Phase II Clinical Trial

Phase II clinical trials are done to study an intervention in a larger group of people (several hundred) to determine efficacy (that is, whether it works as intended) and to further evaluate its safety.

Phase III Clinical Trial

Phase III studies are done to study the efficacy of an intervention in large groups of trial participants (from several hundred to several thousand) by comparing the intervention to other standard or experimental interventions (or to non-interventional standard care). Phase III studies are also used to monitor adverse effects and to collect information that will allow the intervention to be used safely.

Phase IV Clinical Trial

Phase IV studies are done after an intervention has been marketed. These studies are designed to monitor the effectiveness of the approved intervention in the general population and to collect information about any adverse effects associated with widespread use over longer periods of time. They may also be used to investigate the potential use of the intervention in a different condition, or in combination with other therapies.


Clinical trials follow a plan, or set of rules, known as a protocol to ensure that they are as safe as possible, that they measure the right things in the right way and that the results are meaningful. For example, a protocol describes:

  • who is eligible to take part in the trial;
  • the research methods, tests and procedures that will be used;
  • the interventions that will be used and how they will be delivered; and
  • the length of the study, what information will be collected and any follow up.
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There are many reasons why people choose to join a clinical trial. Some join a trial because the treatments they have tried for their health problem did not work. Others participate because there is no treatment for their health problem. By being part of a clinical trial, participants may find out about new treatments before they are widely available. Some studies are designed for, or include, people who are healthy but want to help find ways to prevent a disease, such as one that may be common in their family.

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Clinical trials follow a plan, or set of rules, known as a protocol to ensure that they are as safe as possible, that they measure the right things in the right way and that the results are meaningful. For example, a protocol describes:

  • What is this study trying to find out?
  • What treatment or tests will I have? Will they hurt? Will you give me the test or lab results?
  • What are the chances I will get the experimental treatment or the placebo?
  • What are the possible risks, side effects, and benefits of the study treatment compared with my current treatment?
  • How will I know if the treatment is working?
  • How long will the clinical trial last?
  • Where will the study take place? Will I have to stay in the hospital?
  • Will you provide a way for me to get to the study site if I need it, such as a rideshare service?
  • Can I do any part of the trial with my regular doctor? Is there a closer clinical trial to me?
  • How will the study affect my everyday life?
  • What steps ensure my privacy?
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Medical Care

  • How will you protect my health while I am in the study?
  • What happens if my health problem gets worse during the study?
  • Can I take my regular medicines while in the trial?
  • Who will be in charge of my care while I am in the study? Will I be able to see my own doctor?
  • How will you keep my doctor informed about my participation in the trial?
  • If I withdraw, will this affect my normal care?

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Costs and Reimbursement

  • Will being in the study cost me anything? If so, will I be reimbursed for expenses such as travel, parking, or lodging?
  • Will my insurance pay for costs not covered by the research trial, or will I need to pay out of pocket? If I don’t have insurance, am I still eligible to participate?
  • Will I need a study partner? If so, how long will he or she need to participate? Will my study partner be compensated for his or her time?
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After the Trial Ends

  • Will you follow up on my health after the end of the study?
  • Will you tell me the results of the study?
  • Whom do I call if I have more questions?